The size of the global spatial OMICS market was estimated at USD 176 million in 2020 and is anticipated to grow at a CAGR of 17.5% from 2021 to 2028. To establish a connection between disease and genome architecture, it is essential to comprehend cells and their nucleic acid composition in their morphological context. This will increase translational researchers’ interest in spatial OMICS and related technologies.
The application of spatial transcriptomic and other omics studies has come under scrutiny as a result of the extensive research being done to understand the COVID-19 infection. For instance, to better understand the SARS-CoV-2 infection, a team of researchers from the Massachusetts General Hospital used spatial transcriptomics technology in October 2020 to examine the autopsy samples collected from about 24 COVID-19 patients.
A better understanding of the COVID-19 infection was made possible by the system’s ability to generate enormous data sets of tissue images and molecular data from COVID-19 decedents and compare them to patients who died from diseases like MERS-CoV (2012), SARS-CoV, and other non-viral causes.
The ability to explore spatial information in biological investigation has improved thanks to the development of various in situ methods. Due to the convergence of the structure- and function-focused fields of histology and embryology, as well as the function-oriented fields of biochemistry and molecular genetics, spatially resolved molecular investigation of biological processes is now possible.
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Due to its high utilisation rate and recent product launches, the consumables segment had the largest share (53.1%) in 2020. For instance, Bruker introduced new consumables for the chemical cross-linking of proteins in March 2021. (XL-MS). The XL-MS reaction complex mixtures’ protein purification is made easier by the new PhoX cross-linker. In addition, the business intends to introduce three cross-linkers that can be broken down to release the cross-linkers made during MS experiments.
The creation of the consumables is directly related to the introduction of new instruments. As a result, both the instruments and the consumables segments are driven by this. NanoString announced the creation of a spatial molecular imager in December 2020. (SMI). It is a spatial OMICS platform of the next generation created for multiplexed protein and RNA analysis of single cells in FFPE tissue samples. By 2022, the platform is anticipated to be operational.
With an 89.60% revenue share in 2020, the academic and translational research institutes segment dominated the market. The technology is increasingly being used in translational research to translate real-time tissue reactions to an external agent using spatial OMICS. The behaviour of human tissues and cells from various persons in various contexts can be studied by researchers and healthcare professionals with the aid of translational studies in the field of genomics.
The development of new and improved methods of disease prevention may be facilitated by this crucial information. For instance, neuroscientists have discovered that single-cell transcriptomics is helpful in understanding the many types of brain cells. These techniques aid in comprehending the spatial organisation of nerve tissues and assess the operation of the brain. To do this, it is additionally necessary to relate different molecular cell types to physiological, morphological, and behavioural elements.
Some prominent players in the global spatial OMICS market include:
Key participants profiled in study and leveraging market growth include PerkinElmer, Inc., Dovetail Genomics, IonPath, Inc., Nanostring Technologies, Inc., Seven Bridges Genomics, Danaher Corporation, Bio-Techne, Akoya Biosciences, Inc., Diagenode Diagnostics, S2 Genomics, Inc., Biognosys AG, Vizgen Corporation, Bruker Corporation, Brooks Automation, Inc., BioSpyder Technologies, and Rebus Biosystems.
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